The MIMOSA Package

نویسنده

  • Greg Finak
چکیده

In a vaccine trial setting, intracellular cytokine staining assays measure whether individuals respond to a vaccine. They do so by measuring how antigen-specific T–cells respond to antigen stimulation. Antigen-specific T–cells that respond to antigen express one or multiple cytokines (i.e., IFNg, IL2, TNFa, IL4). The strength of response is measured as the fraction of antigen-specific T-cells expressing the cytokine or cytokine combination, usually relative to an unstimulated control sample.

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تاریخ انتشار 2016